The sample included 1821 adolescents and young adults (874 males and 947 females) between 12 to 25 years of age (see Table 1) and was derived from the prospective sample [72] of the COGA study [73,74]. The sample included offspring of the high-risk (multiple alcohol dependent adult family members) and comparison (community) families ascertained in previous phases of COGA. Participants are reassessed every two years with clinical, behavioral and neurophysiological assessments. Data from the six collection centers have been included in this study. Recruitment and assessment procedures have been described elsewhere [73,75–77], and are also available at this website: https://zork5.wustl.edu/coganew/data/instruments.html. Details regarding access to COGA data are available through the National Institute of Alcoholism and Abuse at http://www.niaaa.nih.gov/research/major-initiatives/collaborative-studies-genetics-alcoholism-coga-study#Access. COGA data are also available from the publically accessible dbGAP database at http://www.ncbi.nlm.nih.gov/gap/?term=COGA [IDs: phs000092.v1.p1, phs000125.v1.p1, and phs000763.v1.p1].
