These ideas about SB further stimulate research aimed at identifying the etiological factors and their effects on the processes of brain and psychological development, leading to a better understanding of the pathophysiology and phenomenology of SB. Hopefully this will help to create tools for the early detection of SB and new strategies for targeted prevention. With this aim in mind, the search for endophenotypes represents a valuable emerging strategy for the identification of susceptibility genes and should improve insight into relevant biological systems, sub-classification of patients and treatment approaches.14, 15
