Based on previous findings suggestive of sex-limitation, we also re-ran the analyses separately for males and females for Harm Avoidance and Reward Dependence. These estimates (see Supplementary Table 6) did not differ substantially from those in Table 3. We also tested for heterogeneity of the estimates from the different subsamples - the estimates from individual subsamples were very imprecise and varied widely, but a formal test revealed no significant heterogeneity (p>0.1 for all scales).