In addition to the measures presented in Table 2, the database will be enriched with information on offspring of the TRAILS cohort. Starting in January 2015, we will monitor TRAILS participants and their partners during any pregnancy, and measure offspring development at 3, 24 and 48 months. Regarding offspring development, the focus will be on temperament, social competence, neurodevelopment and early signs of psychopathology. Social factors will include parental investment, parent-child interactions, socioeconomic position, family structure, life events and difficulties, and social support.