these eQTLs might therefore also be present in other, non-blood tissues, as previously observed for rodents [47]–[49]. Indeed we could replicate some of these trans-eQTLs in a smaller dataset of four non-blood tissues. Importantly, as mentioned before [46], the allelic directions were nearly always identical to blood, which implies that trans-eQTLs, if also present in another tissue, work in the same way.