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Chunk #35 — DISCUSSION

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Genome-wide association analysis links multiple psychiatric liability genes to oscillatory brain activity.
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yes

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The selective hippocampal expression association suggests that the genetic variants affecting beta oscillations also affect hippocampal GABAA receptor's sensitivity to interneuron inhibition. Together, these results indicate that the association between GABRA2 and beta oscillations is more difficult to detect in population‐based samples compared to samples ascertained for alcohol use disorder. In addition, it demonstrates that eQTL based expression analysis increases power to detect associations.