statistic data drawn from the Icelandic population (deCODE) included 3,759 AD cases (65.8 % female) and 8,888 older controls (57.8% females) greater than 85 years of age (for additional details see references 14 and 15). The AD GWAS summary statistic data from the CHARGE consortium were obtained from 4 studies and included 1,315 AD cases (62.1% female) and 21,766 controls (56.9 % female) (for additional details see reference 27). The AD GWAS summary statistic data drawn from the Norwegian population (Oslo) included 434 individuals classified as AD or mild cognitive impairment (57% female) and 1,830 controls (49% female) (for additional details please see Supplemental Information).