We examined the effects of repeated binge drinking by adolescent rats on gene expression in the ventral Hippocampus (vHip) and medial prefrontal cortex (mPFC). The repeated binge exposures between post-natal days 28 to 49 resulted in high average daily ethanol intakes, approximately 8 g/kg/day, with intakes of 2–3 g/kg for each of the 3 daily 1 h sessions for the 5 drinking days each week (McBride, Kimpel, et al., 2014). Blood alcohol levels were not measured in these animals but similarly treated animals reached blood alcohol levels of 80–100 mg% at the end of each 1-hour session (Bell et al., 2011).
