The RVTESTS package incorporates an efficient and powerful variant annotator. To integrate annotation information and other bioinformatics databases, RVTESTS expands VCF files with annotation information and exports resulting datasets, also in VCF format. The integrated dataset is conceptually similar to a master table in a database project, which links sequence variant genotypes to annotation information. The step of preparing sequence data for association analyses is much faster than VAT and PSEQ (Supplementary Table S2).
