Many other explanations to explain the heritability of complex traits have been put forward.72 One of these is that other variants that are currently not captured with the genome-wide SNP platforms (including copy number and rare variants) play a role in explaining variation in personality. Next-generation sequencing may reveal more genetic variants that account for the heritability of complex traits including personality. Nevertheless, identification of genetic variants, even if effect sizes are small, remains an important goal, because these variants can be critical entry points to increased understanding of the biological processes underlying personality as well as psychiatric disorders and other personality-related health, social and behavioral outcomes.
