In summary, almost all of what we presently know about the genetics of human polygenic disorders and quantitative traits has derived from meta-analysis of genome-wide association data. Continued meta-analyses on larger samples are likely to continue to yield useful information. Meta-analysis is also likely to remain a key approach as studies extend into rarer variation, although some methodological changes may be necessary. Consortia or other forms of collaboration are likely to continue to be vital to generate, assemble and analyze large genetic and genomic data sets. The academic community should understand the nature and value of individual contributions to these shared efforts and provide the appropriate academic recognition for collaborative work. Fostering collaboration will continue to enable the shared efforts like meta-analysis of genome-wide association studies that have helped propel human genetics forward over the last several years.
