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Chunk #23 — Methods — MRI data acquisition, processing and statistical analysis — White matter fractional anisotropy and mean diffusivity

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Effects of alcohol use initiation on brain structure in typically developing adolescents.
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SPM8 (www.fil.ion.ucl.ac.uk/spm/software/spm8) was used to perform GLM analysis of relations between FA and MD difference maps and non-brain variables, with cluster-level statistical thresholding of effects maintained at family-wise p < = 0.05 according to corrections derived from random field theory (67).