Considering the rΔF values for each analyzed gene, we observed only two significant outcomes for African ancestry: ZEB1 (Africa rΔF = 0.186; p = 0.005), and HDAC1 (Africa rΔF = 0.316; p = 0.004). These are interactive partners; we did not observe any significant difference for genome-wide significant genes. Supplementary Table 6 shows the top 1% of rΔF values for each ancestry group. Although no ancestry-related differences were observed for the occurrence of RVs in GWAS-relevant genes, high r values in GWAS-relevant genes can be seen in the overall 1KG population (roverall = 0.529 ± 0.215; Table 2).
