Data were obtained from three phases of telephone interviews conducted between 1992 and 2005, as described previously (Hansell et al., 2009). Interviews were adapted from the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA, Bucholz et al., 1994). Lifetime abstainers (i.e. individuals who had never tried alcohol - 2% of those interviewed) were excluded. For 63% of our sample, self-reported ancestry for all grandparents was available. Ancestry was predominantly European with 96% having full European ancestry.