We identified GWA studies with a sample size ≥10,000 in the discovery stage. We used this threshold so as to focus on GWA studies where discovery efforts have had decent power to identify common variants with modest effects (per allele odds ratio >1.20 and minor allele frequency >5%), since with smaller sample sizes many variants with sizeable effects would have been missed and thus there is still substantial uncertainty about the architecture of genetic risks and about what meta-analysis of sufficient data can achieve for the probed phenotypes of interest. Subsequently, we accessed the full-text publications and selected those papers that had performed meta-analyses of 2 or more GWA datasets in the discovery stage regardless of any replication efforts. We included meta-analyses in populations of different ancestries as separate entries. When 2 or more reports were available for the same trait in the same population ancestry, we included the one having the largest sample size.
