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Chunk #36 — Discussion

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Resting-state quantitative electroencephalography reveals increased neurophysiologic connectivity in depression.
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[75]. This wide range of cognitive activities overlaps with the cognitive domains and functions that have been reported to be deficient in some subjects with MDD [3], [79]. Theta oscillations play a significant role in memory function, with modulated coupling of theta oscillations between the prefrontal, parietal, and temporal cortices prominently involved in memory encoding and recall [80]–[82]. In the present study, those edges showing significantly increased coherence in the theta band involved connections between prefrontal and temporal regions. These connections may have special functional significance related to memory dysfunction in MDD, and should be explored in future studies.