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Chunk #15 — Results — Preliminary analyses and descriptive statistics

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Assessment of a modified DSM-5 diagnosis of alcohol use disorder in a genetically informative population.
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The proportion of the sample endorsing each AA and AD criterion is reported in Table 1. Nearly one-third (30.6%, N=2281) of the sample met formal criteria for either AA (11.7%, N=875) or AD (18.9%, N=1406); most (88.8%, N=1248) AD cases also endorsed at least one AA symptom. A slightly larger proportion of the sample met lifetime DSM-5 AUD criteria (32.1%, N=2398). This increase disproportionately affects women, for whom the prevalence increases from 16.9% to 18.8%; for men, these proportions are higher but change less (from 41.4% to 42.7%). The prevalence difference is due to two groups: i) individuals who endorsed only 1 AA symptom, met criteria for AA, but do not meet criteria for AUD (D4-only); and ii) individuals who endorsed 2 AD symptoms and 0 AA symptoms, and therefore meet AUD criteria but not AA or AD criteria (D5-only). The proportions of the sample in each group, including D4D5 (those meeting both DSM-IV and DSM-5 criteria) and those who are unaffected under both sets of criteria, are depicted in Figure 2.