paperKB
coga / coga-kb
Processing
Help
Sign in

Chunk #6 — Introduction

Source
Linking genes, circuits, and behavior: network connectivity as a novel endophenotype of externalizing.
Embedded
yes

Text

Korponay et al., 2017), we hypothesized that the externalizing PS may also moderate network resting-state connectivity and organization in ventral striatum and amygdala. Two graph properties were examined: Participation Coefficient indexes the extent to which a node is a ‘connector hub’ that bridges different functional modules, and Within-Module Degree Z-Score or the extent to which a node is a ‘provincial hub’ that facilitates communication within its own module (Power et al., 2013). We limited our analysis to Participation Coefficient and Within-Module Degree Z-Score, because these centrality metrics that are particularly relevant for identifying hubs that integrate information between and within functionally-distinct subnetworks.