Convergent evidence has suggested that the reduced risk for alcohol dependence seen in African Americans with ADH1B*3 alleles may be in part due to differences in alcohol metabolism (Scott & Taylor, 2007). Results of this study provide the first test of behavioral and physiological differences in those with ADH1B*3 alleles following alcohol consumption. Further research is required to more fully understand the role that ADH1B*3 and response to alcohol play in determining alcohol use topography and alcohol dependence risk in African Americans.
