These ten subsets of expression probes were then analyzed for statistical enrichment of Gene Ontology (GO) terms for Biological processes using all 7,305 expressed probes as a background list. The up-regulated probes in LCLs and the down-regulated probes of the B-cell CD20 samples (with an overlap of 50% of probes) revealed an enrichment of alcohol metabolic process (GO:0006066, False Discovery Rate (FDR) P = 2.0*10-7 and FDR P = 0.03) (see Additional file 2).
