Chunk #33 — The delta opioid receptor gene (OPRD1)

Source

The genetics of the opioid system and specific drug addictions.

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yes

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Delta opioid receptors bind enkephalin as its endogenous ligand. Delta opioid receptors have been implicated in the modulation of reward, addiction, affective state, pain perception, and analgesia. A blunted ability to form and/or retrieve drug-context associations was shown in Oprd1−/− mice (Le Merrer et al. 2011).