Chunk #69 — Online Methods — Identification and evaluation of candidate tumor purity and ploidy values

Source: Absolute quantification of somatic DNA alterations in human cancer.
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The final calculation of the SCNA-fit log-likelihood for each mode is obtained by inserting μ̂, θ ^, and σ̂H into eq. (5). Estimates of the copy-state indicators for each segment are calculated as: