Adolescents with either the DRD4 7− or 7+ genotype showed similar direct effects of couple conflict on threat appraisals (β = .21 and β = .20, respectively). Thus, irrespective of genotype, couple conflict influenced adolescents’ appraisals of threat. In addition, couple conflict was positively associated with adolescent conflict perception for both genotypes (β = .32, β = .46, 7− and 7+, respectively). Similarly, couple positivity was associated with adolescent perception of positivity for both genotypes (β = .37, β = .23). Last, higher couple conflict was associated with lower adolescent perceived interparental positivity for adolescents of either genotype (β = −19, −.24). Only the 7− adolescents showed a significant relation between couple positivity and adolescent perceived interparental conflict (β = −.19); 7+ adolescents showed no association (β = −.06). The difference between these paths was not significant, however, Δχ2(1) = 1.37, ns.