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Chunk #2 — Introduction

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Impulsiveness and insula activation during reward anticipation are associated with genetic variants in GABRA2 in a family sample enriched for alcoholism.
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Impulsivity is a multidimensional behavioral construct which includes at least four different component traits: urgency, sensation seeking, lack of premeditation and lack of perseverance 26. Urgency (called Impulsiveness in the NEO-PI27) is related to the development of alcohol problems that are motivated by a coping strategy involving use of alcohol to deal with emotional distress, often with disregard for negative consequences 28.