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Chunk #4 — 1. Introduction

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Ethanol reduces the phase locking of neural activity in human and rodent brain.
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Cognitive and behavioral processes most likely involve the coordination of a large number of neurons into assemblies that are in communication within individual brain areas as well as across different subsystems (Damasio, 1990; Neuenschwander et al., 1996; Sejnowski, 1986; Singer 1990, 1993). Recent studies suggest that this may be indexed by stimulus-dependent neuronal synchronization (phase locking) of EROs. Phase locking of EROs can be measured in both humans (Sauseng and Klimesch, 2008; Roach and Mathalon, 2008) and more recently in rodent models (Criado and Ehlers, 2009, 2010a, 2010b; Ehlers and Criado, 2009), allowing for translational studies to be conducted.