In summary, the current study provides the first evidence that the ASQ is a reliable predictor of a variety of subjective effects of alcohol measured in the lab. Moreover, the current data suggest differing strengths for the ASQ and SRE. While both ASQ and SRE scores reflect sensitivity to pharmacological effects of alcohol beyond what is accounted for by typical alcohol use, model comparisons indicated that the ASQ outperforms the SRE in predicting post-consumption changes in stimulation and sedation but the SRE is preferred for predicting a simpler subjective intoxication index. The current results go beyond previous findings by assessing the validity of both the SRE and the ASQ in the same sample, using a statistical technique well suited for this purpose and appropriate for the structure of the data. These findings have implications for research into the risk profile characterized by differential sensitivity to acute effects of alcohol. Wide use of this instrument will allow researchers to understand how sensitivity to both stimulant and sedative effects work dynamically to indicate risk for AUD and related problems.
