DNA samples from 188 Hapmap and 1000 Genomes Project participants from CEPH/Utah, Yoruba in Ibadan, Nigeria, and Japanese in Tokyo, Japan populations were obtained from Coriell Institute for Medical Research (Camden, NJ); 442 study samples from NIDA-funded Investigators, and six positive controls provided by the genotyping lab, were obtained for the genotyping pilot (see Table 5).Table 5Smokescreen pilot genotyping sample characteristics - blood or cell lineStudyDescriptionSamplesIndividualsDNA Source%MaleHapmap and 1000 GenomesCEPH/Utah; Yoruba in Ibadan, Nigeria; Japanese in Tokyo, Japan samples188188cell line50.00 %PKTWIN, “588”, SMOFAMNicotine metabolism laboratory studies343326blood45.71 %Total Exposure StudyCross sectional study of tobacco exposures3332blood56.25 %MA fMRI, Modafinil, ASCC2, ASCC Neural SystemsGenetics and brain structure in smokers3534blood58.82 %COGENDReport of genetic results in smokers3130blood33.33 %Positive lab controls61cell line
