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Chunk #8 — Materials and methods — Subjects and phenotyping

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Ethnic diversity of DNA methylation in the OPRM1 promoter region in lymphocytes of heroin addicts.
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In the study sample that was used to determine DNA methylation levels, those subjects with a correlation cutoff ≥0.7 (see below), 24% of the African-American former severe heroin addicts also had a history of alcohol dependence (24 of 100) and 21% of the Hispanic former severe heroin addicts had a history of alcohol dependence (25 of 120).