Given the association of DRD4 with attentional processes, caregiver genotype could be consequential for degree of change in intervention-targeted parenting. To test this possibility, we conducted an exploratory examination of parents’ own genotypes as a factor in their response to the intervention. The results are summarized in Table 3. Significant main effects emerged for both participation in SAAF (γSAAF = .82, p < .05) and parent genotype (γ g = - 1.10, p < .01). The interaction of SAAF with parent genotype approached significance (γS×G = -1.31, p < .10). As Figure 1 shows, caregivers with the 7-repeat allele reported less change in intervention-targeted parenting behavior than did caregivers with two copies of the 4-repeat allele. The marginal interaction was driven by the significant impact of SAAF on the slope of change among parents with 4-repeat alleles (γSAAF = 1.40, p < .01), with no significant effect for parents with a 7-repeat allele (γSAAF = .19, NS).
