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Chunk #10 — MATERIALS AND METHODS — SUBJECT INFORMATION — STATISTICAL ANALYSIS

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The dopamine receptor D2 (DRD2) SNP rs1076560 is associated with opioid addiction.
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A power analysis was conducted using Genetic Power Calculator (Purcell et al., 2003). Using a dominant test this study had 92% power to detect an association with an odds ratio of 1.3 and a minor allele frequency of 12% (α=0.05). Using recessive, genotypic and allelic tests the power to detect association was 12%, 87% and 90% respectively (α=0.05).