is located predominately in peripheral immune cells and organs (Munro et al., 1993), CB2 receptors are also expressed by microglial cells in injured, infected or inflamed CNS tissue (Benito et al., 2008). There is also recent evidence that cannabinoid CB2 receptors exhibit limited neuronal expression (Van Sickle et al., 2005) and are present in neural progenitor cells within the hippocampus (Palazuelos et al., 2006).
