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Chunk #0 — Methods — Participants

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Frontally mediated inhibitory processing and white matter microstructure: age and alcoholism effects.
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Included in this analysis were ten alcoholics with contemporaneously collected EEG and DTI data and 25 age- and sex-matched controls. Demographic, behavioral, and cognitive data were collected within 1 week of ERP collection and appear in Table 1. Of the ten alcoholics, seven had ERP and DTI examinations within 1 day of each other, and three had the two sessions 4, 15, and 17 days apart. Of the 25 controls, 16 had both examinations within 18 days, 4 had a 1 to 6 months lag, and three had about a year lag. Table 1Group characteristics: mean (±SD) or frequency countControlAlcoholic t test p valueMen, women12, 135, 5n.s.Age56.5 (12.81)53.1 (9.05)n.s.Socioeconomic status (SES)a 21.6 (8.14)27.3 (12.61)n.s.Handednessb 17.3 (4.00)24.2 (16.00)0.055Body mass index25.3 (4.27)30.5 (6.78)0.0215Lifetime alcohol consumption (kg)53.8 (64.7)741 (630.0)0.0001NART IQ115.9 (5.45)113.8 (7.36)n.s.Dementia rating scalec 139.9 (3.47)139.8 (139.8)n.s.WASIVIQ115 (8.93)112.6 (10.36)n.s.PIQ121.6 (12.59)108.9 (15.48)0.017FSIQ120.8 (11.0)113.8 (11.2)n.s.WMS-RGeneral memory index121.1 (13.04)123 (12.62)n.s.Attention index110.2 (11.08)108.5 (19.23)n.s.The NART score is an estimated premorbid IQ from the National Adult Reading Test (Nelson 1982). The WASI is the Wechsler Abbreviated Scale of Intelligence (Wechsler 1999), which provides estimates of Verbal (VIQ), performance