Chunk #28 — DISCUSSION — 18q23, Neural Connectivity, and Neurocognitive Dysfunction

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A genome-wide association study of interhemispheric theta EEG coherence: implications for neural connectivity and alcohol use behavior.

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As noted above, GABRA2 has been linked to resting-state beta oscillatory power in both an earlier iteration of the COGA study16, as well as in independent samples15. We note that GABRA2 SNPs were nominally associated with low theta coherence (p<0.05) in the current study, however this p-value did not withstand multiple test correction.