To empirically assess the specificity of the ADH1B variant-alcohol intake associations, the OR of selected participant's and partner's characteristics were derived comparing carriers of the rs1229984 A allele versus non-carriers, and those drinking <1 unit/week before pregnancy versus those drinking ≥1 units/week (Supplementary Material, Table S4). Similarly, since abstaining in the first trimester could be explained by symptoms of nausea and food aversions, we looked at these in association with rs1229984 (Supplementary Material, Table S5).
