The most robust electrophysiological findings in alcoholism are related to the P3 component (Porjesz et al. 2005), a large positive going wave that occurs between 300 and 600 ms after the stimulus (Duncan et al. 2009; Sutton et al. 1965). P3 is not related to the physical characteristics of the stimulus but is related to its “significance” and is an index of various neurocognitive processes, including attention and working memory (Donchin 1981; Kok 2001; Polich 2007; Verleger 1988).
