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Chunk #19 — Results — Associations of DNA Methylation with Physical Aggression in the Loci of Transcriptional Regulators of Differentially Expressed Cytokines

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Differential DNA methylation regions in cytokine and transcription factor genomic loci associate with childhood physical aggression.
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regions associated with CPA within the NFkB locus, 21 of these regions were located within the gene body (Figure S4). In the NFAT5 locus, 19 differentially methylated regions between CPA and controls were identified and all of them except one were located within the body of the gene (Figure S5). A total of 10 regions were identified in STAT6 locus, two of the differentially methylated regions associated with CPA were found in T cells and all other differentially methylated regions associated with CPA in STAT6 were found in monocytes (Figure S6).