create an atlas of concordance and shed light on the sensitivity and specificity of these genetic methods. One final critique of this approach is that it falls short of identifying plausible genetic and biological mechanisms that mediate potentially pleiotropic loci. Future work incorporating expression quantitative trait loci, differentially expressed or methylated genes, or enriched ontological and functional terms may provide a clearer context for assessing biological similarities between phenotypes. Despite these limitations, the present study indicates that shared aspects of common genetic variation may underlie long-recognized epidemiological links between psychiatric and immune-related disorders and serves as a start point for the identification and characterization of potentially pleiotropic loci.
