Multiplex familial high risk status increased the odds that 8–11 year old children would have an externalizing disorder (odds ratio = 6.12, q =0.024). The likelihood that offspring would experience some form of psychopathology before the age of 12 was elevated in association with maternal alcoholism (odds ratio = 3.43, q = 0.024). These children of AD mothers showed an increased risk for externalizing disorders (odds ratio = 4.23, q = 0 .024) that was not seen in offspring of alcohol dependent fathers (Table 3). Interestingly, parental drug dependence or depression (neither or either parent affected) did not appear to increase risk for externalizing or internalizing psychopathology in childhood. When analyzed separately by parent, mother or father, none of the comparisons were significant for presence of an internalizing disorder in young children.
