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Chunk #4 — Methods — Overview

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A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010.
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The basic approach for the GBD 2010 comparative risk assessment is to calculate the proportion of deaths or disease burden caused by specific risk factors—eg, ischaemic heart disease caused by increased blood pressure—holding other independent factors unchanged. These calculations were done for 20 age groups, both sexes, and 187 countries and for 1990, 2005 (results for 2005 not shown, available from authors on request), and 2010. We present aggregated results for 21 regions.