Of the 697 SNPs, 403 were represented on the Metabochip array9. Using data from 80,067 individuals genotyped on the Metabochip array from 37 independent studies, we observed very strong evidence of concordance of effect sizes between the Metabochip and GWAS samples (P = 1.9×10−160); and >99% of variants were directionally consistent between Metabochip and GWAS (Online Methods, Supplementary Note, and Supplementary Table 3).
