In meta-analyzed cross-ancestry findings from the primary regression models, lifetime CUD diagnosis was strongly associated with reporting cannabis-related experiences (P < 8.3e−26; table 3). Similar associations were noted for earlier age at first cannabis use and cannabis-related experiences (P < 2.2e−4). Duration of daily cannabis use was significantly associated with all experiences (P < 2.9e−5) except hallucinations and paranoia. We also found that CUD severity (as coded in the DSM-5: mild, moderate, severe, or none) was strongly associated with endorsement of a greater number of cannabis-related experiences (ANOVA F-statistic = 783.1 (3, 3039.1), P < 2e−16 in the European ancestry sample; F-statistic = 351.7 (3, 1639.0), P < 2e−16 in the African ancestry sample; note: degrees of freedom are not always integer values because they were estimated using Satterthwaite’s method of approximation).
