target populations, we used an independent dataset of ~39,000 UKB individuals. Those individuals included the 10,000 randomly sampled participants who identified themselves as British, 9979 participants of EUR who identified themselves as Irish, the 9448 participants of SAS, the 2257 participants of EAS and the 7015 participants of AFR. Data from the 1KGP were used as the reference panel in this study. We generated subsets of unrelated individuals in 1KGP with the same strategy as described above, resulting in 495 EUR, 457 SAS, 498 EAS and 484 AFR.
