Chunk #1 — Background

Source: Molecular genetics of nicotine dependence and abstinence: whole genome association using 520,000 SNPs.
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Phenotypes relating to successful abstinence from smoking have also been studied in twin samples [10,11]. Success at achieving smoking abstinence displays heritability in the range of 40 – 60%. Some of this heritable component appears to overlap with heritable features of nicotine dependence and some does not.