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Chunk #12 — Materials and methods — SL for EEG connectivity

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Disturbed resting state EEG synchronization in bipolar disorder: A graph-theoretic analysis.
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SL was computed between all pairs of EEG channels in each frequency band as a measure of functional connectivity across time and electrode sites. SL measures generalized synchronization and can detect both the linear and nonlinear inter-dependences between two signals (Stam and van Dijk, 2002). We provide a brief description of its calculation and the strategy for optimal parameter selection in the supplementary material. The result of computing SL for each EEG channel of a specific frequency band is a 29 × 29 matrix where 29 is the number of EEG channels in this study. This weighted matrix provides the basis for computation of network properties among electrode sites. A schematic overview of processing and analysis is shown in Fig. 1.