Blood oxygenation level dependent (BOLD) contrast sensitive functional imaging was conducted with a 12-channel head coil array on a Siemens 3T Magnetom Trio-Tim scanner (Erlangen, Germany). A whole-brain high-resolution anatomic image volume (1.0×1.0× 1.2 mm3 voxels) was first collected using a 3D magnetization prepared rapid gradient echo (MPRAGE) sequence for anatomic registration of the functional images. For each functional scan, 189 BOLD volumes were acquired in 6:54 min using an echo-planar imaging pulse sequence (gradient echo; 2250/29 ms repetition/echo time, 78° flip angle, 88 × 88 matrix, 2.5×2.5×3.0 mm3 voxels, 39 slices, GRAPPA acceleration factor 2) that incorporated a 3D prospective acquisition correction to minimize effects of the head motion (Thesen et al., 2000).
