Chunk #14 — RESULTS — DS-epi1 is important for cranial neural crest cell migration

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Musculocontractural Ehlers-Danlos syndrome and neurocristopathies: dermatan sulfate is required for Xenopus neural crest cells to migrate and adhere to fibronectin.

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A TUNEL assay demonstrated that the Dse-MO had no detectable effect on apoptosis at the neurula or early tailbud stage; however, it induced cell death in advanced tailbud embryos (Fig. S6). The data indicate a distinct role of DS-epi1 in CNC cell migration.