Chunk #11 — MATERIALS AND METHODS — Genotyping and quality control

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The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.

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Genotype data were then combined for this new sample and the previously genotyped sample of 1608 EAs. Allele correspondence was checked. All association analyses are reported using the major allele in the EA sample as the reference allele.