(through reduction of some of the multiple testing burden in standard GWAS). More information on the usage of the interactome data and the visualization of the resulting networks are found in the supplementary material and methods. In brief, we would like to emphasize that our analyses represent a simple, hypothesis driven approach for inclusion of the human interactome data, rather than an exhaustive network science approach (making use among others of topological features of the interactome other then the status of direct interaction). While the latter has been successfully used with neuropsychiatric traits in the past, we felt that this evolving field still needs some further improvements and therefore decided to refrain from these kinds of analyses.
