There is some ERP evidence to suggest that schizophrenia patients exhibit abnormally long IHTTs to unilaterally-presented visual stimuli (Barnett et al., 2005; Barnett and Kirk, 2005; Endrass et al., 2002). If these IHTT abnormalities are indeed underpinned by physical damage to the white-matter fibers connecting the visual cortices bilaterally, then schizophrenia patients might be expected to show DTI abnormalities in the visual fibers of the corpus callosum. However, while a number of studies have identified diffusion abnormalities in the splenium of the corpus callosum (Cheung et al., 2008; Foong et al., 2000), including in fist-episode, antipsychotic-naïve patients (Gasparotti et al., 2009), there have been no studies (to our knowledge) that have either used DTI to investigate the structural integrity of the visual callosal fibers explicitly in schizophrenia patients, or have investigated the relationship between IHTT and the integrity of the visual callosum fibers in schizophrenia patients. Indeed, despite the established qualitative relationship between the integrity of the corpus callosum and interhemispheric transfer, as evidenced by the IHTT abnormalities exhibited by acallosal individuals; (Bayard et al., 2004), only one previous study
