In unweighted networks, ClusterCoefi equals 1 if and only if all neighbors of gene i are also linked to each other. For weighted networks, 0 ≤ aij ≤ 1 implies that 0 ≤ ClusterCoefi ≤ 1 [5]. The mean clustering coefficient has been used to measure the extent of module structure present in a network [26,34].
